Give vitamin D in patients with painful diabetic neuropathy. Lower vitamin D levels are found in patients with painful diabetic peripheral neuropathy (DPN) compared to those with painless DPN, patients with diabetes without any neuropathy, and healthy people.
President HCFI Padma Shri Awardee Dr KK Aggarwal wrote in a newsletter.
“The findings have major clinical significance because painful DPN is distressing and disabling. 25% of DPN patients have pain and most are undiagnosed and suffer in silence because they believe it is just part of the aging process," said lead author Solomon Tesfaye, MD, consultant endocrinologist at the Royal Hallamshire Hospital, Sheffield, UK.
The small proof-of-principle study was a borne out of anecdotal findings that vitamin D supplements or injections given to patients with painful DPN improved their pain.
According to the research article, Study addressed limitations and evaluated vitamin D levels in people with carefully phenotyped diabetic peripheral neuropathy and controls.
The article was published online August 13, 2018 in Diabetic Medicine. Researchers are P. Shillo D. Selvarajah M. Greig R. Gandhi G. Rao I. D. Wilkinson P. Anand and S. Tesfaye.